Tag: cell
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Targeting myosin II to alter the disease course of challenging diseases
The field of cell mechanobiology, which studies the physical forces that cells experience and generate, is emerging as a critical area for therapeutic intervention in complex and challenging diseases. Non-muscle myosin II (NMII) is a key motor protein involved in various cellular processes, including cell shape, motility, and division, all of which are influenced by…
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Simplifying protein engineering with deep learning
Introduction: The field of protein engineering is undergoing a significant transformation, driven by advancements in deep learning. This analysis delves into the findings presented in a recent publication in Cell, which highlights the efficacy of a simplified approach to protein engineering using deep learning. The core argument is that thoughtful deployment of existing fixed-backbone sequence…
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Interferons in health and disease
Introduction Interferons, a class of cytokine messenger proteins, play a critical role in the immune system, particularly in defense against infections. However, their involvement extends beyond antiviral and antibacterial immunity, encompassing roles in inflammatory and autoimmune diseases. This analysis delves into the multifaceted functions of interferons in animal biology, exploring the delicate balance of factors…